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Treatment Considerations

Who should not use ELOXATIN (oxaliplatin injection)?

Do not use ELOXATIN (oxaliplatin injection) if you are allergic to any of the ingredients in ELOXATIN (oxaliplatin injection) or other medicines that contain platinum. Cisplatin (Platinol®) and carboplatin (Paraplatin®) are other chemotherapy medicines that also contain platinum. For a list of the ingredients in ELOXATIN (oxaliplatin injection), click here.

What should I tell my doctor before treatment with ELOXATIN (oxaliplatin injection)?

Tell your doctor about all your medical conditions including, if you are:

  • Pregnant or planning to become pregnant. ELOXATIN (oxaliplatin injection) may harm your unborn child. You should avoid becoming pregnant while taking ELOXATIN (oxaliplatin injection). Talk with your doctor about how to avoid pregnancy.
  • Breast feeding or plan to breast feed. We do not know if ELOXATIN (oxaliplatin injection) can pass through your milk and if it can harm your baby. You will need to decide whether to stop breast feeding or not to take ELOXATIN (oxaliplatin injection).

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. ELOXATIN (oxaliplatin injection) may affect how other medicines work in your body.

Know the medicines you take. Keep a list of them and show it to your doctor and pharmacist when you get a new medicine.

Important Safety Information

Anaphylactic-like reactions to ELOXATIN have been reported and may occur within minutes of ELOXATIN administration. Epinephrine, corticosteroids, and antihistamines have been employed to alleviate symptoms.

  • Do not take ELOXATIN if you are allergic to any of the ingredients in ELOXATIN or other medicines that contain platinum. Tell your doctor right away if you feel like your throat is closing up, have shortness of breath, a flushed face, a rash, itching/hives, swelling of lips or tongue, sudden cough, dizziness, sweating or chest pain.
  • ELOXATIN can cause nerve problems. Tell your doctor right away if you become sensitive to cold temperatures and cold objects; have trouble breathing, swallowing or saying words; experience jaw tightness, odd feelings in your tongue, or chest pressure; pain; tingling or burning in your hands, feet or around your mouth or throat.
  • Tell your doctor if you develop a dry cough or have trouble breathing; these may be signs of serious lung disease.
  • ELOXATIN can cause liver problems (hepatotoxicity); your doctor will do blood tests to watch for this.
  • Because of the potential risk of fetal harm, pregnant women should not receive ELOXATIN. Women of childbearing potential should avoid becoming pregnant while receiving ELOXATIN.
  • ELOXATIN can cause a decrease in white blood cells, which can lead to infections. Tell your doctor right away if develop any of the following signs of infection: fever, chills, or shivering; cough that brings up mucus, burning or pain on urination, pain on swallowing; sore throat; or redness or swelling at injection site.
  • Other common side effects of ELOXATIN include a decrease in white blood cells, red blood cells, and platelets, nausea, vomiting, diarrhea, and tiredness.
  • Tell your doctor about all the medications you take, including prescription and non-prescription medications, vitamins and herbal supplements.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of ELOXATIN. For more information, ask your doctor or pharmacist.

Please click here for full prescribing information including boxed WARNING.