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Advanced Colorectal Cancer

If you've been diagnosed with advanced colorectal cancer, it's important that both an oncologist and a surgeon are part of your healthcare team. This combined approach will help give you access to surgical techniques, imaging, and chemotherapy treatment. Talk to your healthcare team about whether you’re a candidate for these treatments.

Liver Resection

One of the surgical treatment options that may be right for you if you have liver metastases is called a liver resection. With this treatment, the portion of your liver that has metastatic tumors is surgically removed. Since the liver has the capacity to regenerate, up to 80% of it can be surgically removed. Within several weeks your liver actually has the capacity to regenerate.

Ask your doctor/surgeon team if you’re a candidate for liver resection surgery. Here are some questions you can ask your medical team.

  • Can a complete resection of the liver metastases be performed?
  • Can two side-by-side liver segments be spared?
  • Will I have at least 20% total healthy liver remaining after surgery?
  • Can enough liver function be preserved?

Learn about colorectal cancer treatment options.

Important Safety Information

Anaphylactic-like reactions to ELOXATIN have been reported and may occur within minutes of ELOXATIN administration. Epinephrine, corticosteroids, and antihistamines have been employed to alleviate symptoms.

  • Do not take ELOXATIN if you are allergic to any of the ingredients in ELOXATIN or other medicines that contain platinum. Tell your doctor right away if you feel like your throat is closing up, have shortness of breath, a flushed face, a rash, itching/hives, swelling of lips or tongue, sudden cough, dizziness, sweating or chest pain.
  • ELOXATIN can cause nerve problems. Tell your doctor right away if you become sensitive to cold temperatures and cold objects; have trouble breathing, swallowing or saying words; experience jaw tightness, odd feelings in your tongue, or chest pressure; pain; tingling or burning in your hands, feet or around your mouth or throat.
  • Tell your doctor if you develop a dry cough or have trouble breathing; these may be signs of serious lung disease.
  • ELOXATIN can cause liver problems (hepatotoxicity); your doctor will do blood tests to watch for this.
  • Because of the potential risk of fetal harm, pregnant women should not receive ELOXATIN. Women of childbearing potential should avoid becoming pregnant while receiving ELOXATIN.
  • ELOXATIN can cause a decrease in white blood cells, which can lead to infections. Tell your doctor right away if develop any of the following signs of infection: fever, chills, or shivering; cough that brings up mucus, burning or pain on urination, pain on swallowing; sore throat; or redness or swelling at injection site.
  • Other common side effects of ELOXATIN include a decrease in white blood cells, red blood cells, and platelets, nausea, vomiting, diarrhea, and tiredness.
  • Tell your doctor about all the medications you take, including prescription and non-prescription medications, vitamins and herbal supplements.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of ELOXATIN. For more information, ask your doctor or pharmacist.

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